The Circulation Academy


In recent years, there has been significant interest across various therapeutic areas using Temperature Management.
THE CIRCULATION ACADEMY offers clinicians and healthcare professionals a curated resource center of new and groundbreaking contributions to the conversation of Temperature Management.

This site is for education, science, medicine and discussion on temperature management topics and not all of which may be cleared by the FDA.

Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest; Nielsen 2013
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Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm; Lascarrou 2019
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A Systematic Review of Therapeutic Hypothermia for Adult Patients Following Traumatic Brain Injury; Crossley 2014 of therapeutic hypothermia for adult patients following traumatic brain injury; Crossley 2014
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Feasibility and Safety of Intravascular Temperature Management for Severe Heat Stroke: A Prospective Multicenter Pilot Study; Yokobori 2018
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Targeted temperature management (TTM) refers to strict temperature control following Sudden Cardiac Arrest (SCA). Historically referred to as “therapeutic hypothermia” or maintaining normothermia, prior evidence suggested targeted temperature management following sudden cardiac arrest may improve neurologically intact survival with a number of proposed mechanisms.

Professional guidelines from the AHA and ERC continue to recommend therapeutic hypothermia of between 33-36°C for 24 hours, and normothermia for at least 72 hours after ROSC with In-Hospital Cardiac Arrests (IHCA) and Out-of-Hospital Cardiac Arrests (OHCA).

Cardiac Resources and Tools

Listen to industry leaders with our on-demand webinars & podcasts. Access educational resources for you and your team. Access recent & relevant publications in our curated clinical library


Observational studies have shown fever to be a critical predictor of adverse neurological outcomes and mortality in ischemic stroke, traumatic brain injury, post-anoxic injury, subarachnoid hemorrhage, and intracranial hemorrhage. (Azzimondi et al. 1995; Castillo et al. 1998; Hajat et al. 2000; Kammersgaard et al. 2002; Polderman 2008; Reith et al. 1996; Schwarz et al. 2000). 

Neurocritical Care Resources and Tools

Targeted temperature management (TTM) is a clinical treatment strategy to control core body temperature (target temperature) for a certain duration. Proponents theorize that in some clinical situations doing so may reduce secondary brain injury.


Extreme environmental conditions such as heatstroke and environmental hypothermia, are medical emergencies with multiple organ involvement and life-threatening illness. Uncontrolled damage to the central nervous system can result in severe cerebral edema, permanent neurological sequelae, and death. The management of environmental conditions is discussed.

Environmental Temperature Management Resources and Tools

Find educational resources and publications focused on environmental factors.

Inaugural Steering Committee

The Circulation Academy Steering Committee is led by a multidisciplinary group comprised of physician leaders with deep clinical and operational knowledge of temperature management in the critical care setting. The group carefully curates a selection of research papers, educational tools and conversations to inform, guide and support knowledge of temperature management across various applications.

Benjamin S. Abella, MD

Emergency Medicine

Benjamin S. Abella headshot

Benjamin S. Abella, MD, MPhil is an emergency medicine practitioner, internist, academic and researcher. He is a Professor and Vice Chair of Research at University of Pennsylvania’s Department of Emergency Medicine. He directs the Center for Resuscitation Science and the Penn Acute Research Collaboration at the University. He has participated in developing international CPR guidelines. Dr. Abella has published over 200 scholarly papers regarding cardiac arrest, myocardial perfusion, therapeutic hypothermia, CPR delivery and resuscitation. He is a fellow of the European Resuscitation Council.

Nicholas Johnson, MD

Critical Care & Emergency
UW - Harborview

Nicholas Johnson headshot

Nick Johnson, MD, is a physician in the medical intensive care unit, trauma intensive care unit, ECMO team, and emergency department at Harborview. He is also the UW’s associate program director for the Critical Care Medicine Fellowship and a UW assistant professor of Emergency Medicine and Pulmonary, Critical Care and Sleep Medicine. Dr. Johnson is a member of the American College of Emergency Physicians, Society for Academic Emergency Medicine, Society of Critical Care Medicine and the American Heart Association. Dr. Johnson has been cited over 4000 times for his scholarly work in cardiac arrest, emergency medicine among other areas.

Sarah Wahlster, MD

Neurocritical Care
UW - Harborview

Sarah Wahlster headshot

Dr. Wahlster, MD, obtained her medical degree at the Ruprecht-Karls Universität Heidelberg, followed by a post-doc in Epigenetics of Neurodegenerative Disease at Harvard Medical School. She completed neurology residency and neurocritical care fellowship at MassGeneral/Brigham in Boston. She is now the fellowship director and the section head of Neurocritical Care in the Department of Neurology at University of Washington. Her academic interests include Mechanical Ventilation in Acute Brain Injury, Extubation and Tracheostomy Decisions in the NeuroICU, Long-Term Outcomes of Patients and their Families After Severe Acute Brain Injury, Neuroprognostication after Cardiac Arrest, Neurological Care in Resource-Limited Settings, and Medical Education.


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