CARDIAC
TARGETED TEMPERATURE MANAGEMENT
FOR CARDIAC PATIENTS
Targeted temperature management (TTM) is a complex intervention used with the aim of minimizing post-anoxic injury and improving neurological outcome after cardiac arrest1. Active temperature management at subnormal temperatures has been an important, evidence-based component of adult post–cardiac arrest care for 2 decades, used with the goal of mitigating secondary brain injury in patients who do not follow commands after cardiac arrest (unresponsive)2.
Professional guidelines from the American Heart Association and the International Liaison Committee on Resuscitation continue to evaluate findings from recent publications and their potential impact on the practice of temperature management in the context of overall post–cardiac arrest care.
CLINICAL LIBRARY
Our carefully crafted clinical library provides quick access to several medical resources including the latest guidelines, publications, and whitepapers.
RELEVANT ARTICLES
FROM A VARIETY OF SOURCES
- Temperature Control in Acute Brain Injury: An Update; Lin 2024
- Temperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest; Beekman 2024
- Therapeutic Hypothermia Compared with Normothermia in Adults with Traumatic Brain Injury; Functional Outcome, Mortality, and Adverse Effects: A Systematic Review and Meta-Analysis; Martyniuk 2024
- Cardiac Catheterization Laboratory Management of the Comatose Adult Patient With an Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association; Tamis-Holland 2023
- Temperature control after adult cardiac arrest: An updated systematic review and meta-analysis; Granfeldt 2023
- Temperature control after successful resuscitation from cardiac arrest in adults; Behringer 2023
- 2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support; Perman 2023
- Effects of Hypothermia vs Normothermia on Societal Participation and Cognitive Function at 6 Months in Survivors After Out-of-Hospital Cardiac Arrest; Lilja 2023
- Temperature Management for Comatose Adult Survivors of Cardiac Arrest: A Science Advisory From the American Heart Association; Perman 2023
- Cochrane Review: Hypothermia for Neuroprotection in Adults aer Cardiac Arrest; Arrich et al. 2023
- A Commentary on the Effect of Targeted Temperature Management in Patients Resuscitated from Cardiac Arrest; Holzer 2022
- Targeted Temperature Management in Adult Cardiac Arrest: Systematic Review and Meta-analysis; Granfeldt et al. 2021
- Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest; Dankiewicz 2021
- Time to intra-arrest therapeutic hypothermia in out-of-hospital cardiac arrest patients and its association with neurologic outcome: a propensity matched sub-analysis of the PRINCESS trial; Awad 2020
- Taccone_Crit Care 2020_High Quality TTM
- Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm; Lascarrou 2019
- Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest; Kirkegaard 2015
- Long-term outcomes in elderly survivors of in-hospital cardiac arrest; Chan 2013
- Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest; Nielsen 2013
DOWNLOADABLE WHITE PAPERS
IN PDF FORMAT
ON DEMAND WEBINARS
Understanding the Translational Gap in Post-Resuscitation Care: Temperature Control Parameters Matter
Date: October 2024
Speaker:
TTM in Neuro ICU, Surgical Cases and Medical Cases: Recent Evidence of High Quality TTM
Date: August 2024
Speaker:
Beyond One-Size-Fits-All: The Era of High-Quality Temperature Management
Date: October 2021
Moderator:
Speaker:
A scientifically nuanced look at 36 or 33 °C: Which temperature I would prefer if I were the patient
Date: September 21, 2020
Speaker:
PODCASTS
Listen to the Experts:
Targeted Temperature Management
Moderator :
W. Dalton Dietrich, PhD
Scientific Director, The Miami Project to Cure Paralysis
Senior Associate Dean for Discovery Science
Co-Director, Institute for Neural Engineering
Associate Director, Miami CTSI
Professor of Neurological Surgery, Neurology, Biomedical Engineering, and Cell Biology
University of Miami
Leonard M. Miller School of Medicine
Episode #1: Temperature Management Matters: Past, Present and Future
Presenter :
Nicholas Johnson, MD, FACEP, FCCM
Associate Professor and Head, Section of Critical Care, Department of Emergency Medicine
Associate Professor of Medicine, Division of Pulmonary Critical Care and Sleep Medicine
Associate Program Director, Critical Care Medicine Fellowship
Co-Chair, Code Committee
UW Medicine | Harborview Medical Center
Episode #2: During TTM, What Matters Most
Presenter :
Justin B. Lundbye, MD, FACC, MBA
Senior Vice President and Chief Medical Officer
Waterbury HEALTH
Episode #3: High-Quality TTM Matters to Hospitals
Presenter :
Michael Christopher Kurz, MD MS
Associate Director
Cardiovascular Interventional Center
CVIC Preop/PACU
Smidt Heart Institute at Cedars-Sinai Medical Center
Presenter :
David Hildebrandt BSN, MBA
Professor and Vice-Chair for Research
Department of Emergency Medicine
UAB Medicine | Center for Injury Science
Episode #4: Early Induction of Temperature Management
Presenter :
Prof. Dr. Wilhelm Behringer, MBA (Master of Business Administration), MSc (Master of Science)
Head of the Department for Emergency
Medical University of Vienna
University Hospital of Vienna
Episode #5: Why Do I Use Target Temperature Management?
Presenter :
Brian J. O’Neil, MD, FACEP, FAHA
Munuswamy Dayanandan Endowed Chair
Professor
Wayne State University, School of Medicine
Department of Emergency Medicine
Presenter :
Bernd W. Böttiger, M.D., M.L., D.E.A.A., F.E.S.C., F.E.R.C., F.A.H.A.
Treasurer, European Resuscitation Council (ERC)
Immediate Past Director Science and Research, ERC
Chairman, German Resuscitation Council (GRC)
Federal State Doctor/Medical Advisor, German Red Cross (DRK)
Professor and Head of the Department of Anesthesiology and Intensive Care Medicine
University Hospital of Cologne
Episode #6: The Importance of Fever Prevention in Clinical Practice
Presenter :
Shahed Toossi
Assistant Professor of Neurocritical care, Departments of Neurology and Neurosurgery
Director – Neurocritical Care Fellowship Program
Cedars-Sinai Medical Center
Presenter :
Rainer Lenhardt, MD, MBA
Professor and Vice-Chair for Clinical Affairs
Dept. of Anesthesiology and Perioperative Medicine, Critical Care
University of Louisville
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- Taccone FS, Picetti E, Vincent JL. High Quality Targeted Temperature Management (TTM) After Cardiac Arrest. Crit Care. 2020 Jan 6;24(1):6. doi: 10.1186/s13054-019-2721-1. PMID: 31907075; PMCID: PMC6945621.
- Panchal AR, Bartos JA, Cabañas JG, Donnino MW, Drennan IR, Hirsch KG, Kudenchuk PJ, Kurz MC, Lavonas EJ, Morley PT, O’Neil BJ, Peberdy MA, Rittenberger JC, Rodriguez AJ, Sawyer KN, Berg KM; Adult Basic and Advanced Life Support Writing Group. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2020 Oct 20;142(16_suppl_2):S366-S468. doi: 10.1161/CIR.0000000000000916. Epub 2020 Oct 21. PMID: 33081529.